Our new Medicine at the Crick event series showcases major advances in biomedical science and raises awareness of the medical implications of major scientific advances. Interested members of the Crick and wider UK biomedical community are invited to attend. Members of the academic medical press are also invited. Each event comprises a series of talks and a panel discussion, followed by networking for in-person attendees. 

How can therapeutics target cancer stem cells?

Our 9th event, How can therapeutics target cancer stem cells, will be hosted by Prof Dominique Bonnet (The Francis Crick Institute). 

Tumour heterogeneity represents an ongoing challenge in the field of cancer therapy. Heterogeneity is evident between cancers from different patients and within a single tumour. The latter includes phenotypic diversity such as cell surface markers, (epi)genetic abnormality, growth rate, apoptosis and other hallmarks of cancer that eventually drive disease progression and treatment failure. Cancer stem cells (CSCs) have been put forward to be one of the non-genetic determining factors that contribute to intra-tumour heterogeneity.

In this 9th edition of Medicine at the Crick, we will review our current understanding of Cancer Stem Cells, their role in initiation, progression and chemoresistance. We will also discuss new therapeutic avenues to eradicate these cells.

Speakers include ​​​Prof John Dick (Princess Margaret Cancer Centre, University of Toronto), Prof Axel Behrens (CRUK Convergence Science Centre, Institute of Cancer Research & Imperial College London), Prof Simona Parrinello (UCL Cancer Institute) and Prof Jeremy Rich (UPMC Hillman Cancer Center).

We will host this as a hybrid event with a limited in-person audience joined by others online. Please register now for a free virtual or in-person ticket. Virtual ticket holders will receive Zoom joining details in advance of the webinar and in-person ticket holders will be emailed with full attendance details nearer the event.

The safety of our staff and visitors is our priority and we have measures in place to ensure this is a Covid-19 safe event.

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