The CrickConnect team are delighted to be able to invite community members to join us for the institute's regular Crick Lecture.

Crick Lectures provide a broad insight into biomedical research from leading scientists. Not to be missed, the one-hour lectures are the event of the week for the Crick community to come together. 

Crick Lectures take place weekly (usually on Thursday at 16:00), and are given by leading scientists. The lectures aim to be accessible to scientists across different disciplines, while also offering something for the specialist.

Due to the pioneering and sensitive nature of some of the research discussed in these lectures, only Crick Lectures from selected speakers will be shared, and we ask all attendees to respect the private nature of these talks by refraining from making any type of recording, sharing access details or in any other way compromising the research that is discussed.

Speaker Profile

For this weeks lecture we are delighted to welcome alumni Martin Turner to speak. Martin joined Crick founding insitute the NIMR with Victor Tybulewicz and now joins us from the Babraham Institute as a molecular biologist and Head of the Lymphocyte Signalling & Development Laboratory. 

Turner has focused on the interface between immunology and molecular biology, producing key insights into immune disease and therapies.

As a student, with Marc Feldmann he carried out the first systematic application of molecular biology to cytokine gene-expression in healthy and diseased human cells. His findings on T-cell TNF production and TNF activation of IL-1 and IL-6 expression contributed to the concept of anti-cytokine therapy.

Turner made essential contributions to the understanding of antigen receptor signaling in the development, homeostasis and activation of lymphocytes, providing broader insights into signal transduction by diverse receptor types. He discovered essential roles for guanine nucleotide exchange factors and phosphoinositide 3-kinase-delta in lymphocytes, providing the underpinning rationale for PI3K inhibition in B cell diseases.

Turner is currently focused on post-transcriptional regulation of gene expression and cell fate in the immune system. He discovered that miR155 is essential for immunity and identified its targets and mechanisms of action in lymphocytes. He has coupled mouse models with systematic transcriptomic and RNA/protein binding analyses to uncover widespread roles of RBPs in lymphocyte biology, highlighting the central role in lymphocyte differentiation and function.